Welcome to Global Peptides Lab, your trusted global source for high-purity research materials. Our flagship CJC-1295 No DAC 10mg (frequently recognized in scientific literature as modified GRF 1-29) is meticulously synthesized to support advanced endocrinology studies, cellular signalling pathway investigations, and growth hormone-releasing hormone (GHRH) receptor dynamics. Designed exclusively for professional laboratory environments, this compound provides researchers with a stable, highly consistent, and well-characterized peptide structure optimized for complex in vitro and preclinical models.
The Scientific Significance of GHRH Analogues Without DAC
In contemporary peptide synthesis and endocrine research, understanding the structural nuances of growth hormone secretagogues is paramount. Natural growth hormone-releasing hormone is notoriously short-lived in physiological fluids due to rapid enzymatic degradation. To overcome this limitation, scientific innovators developed modified analogues. The variant supplied by Global Peptides Lab lacks the Drug Affinity Complex (DAC) extension. Without this complex binding to serum albumin, CJC-1295 No DAC 10mg exhibits a shorter, more natural half-life (typically around 30 minutes), which closely mimics the body’s endogenous, pulsatile secretion patterns.
This characteristic makes it an invaluable tool for researchers aiming to observe discrete secretory pulses, receptor-binding affinities, and downstream signaling cascades without the continuous pharmacokinetic presence associated with long-acting DAC variants. Investigators can precisely measure peak responses, cellular feedback loops, and receptor cross-talk within controlled laboratory timelines.
Technical Specifications & Characteristics
To facilitate precise calculations and experimental reproducibility, our vials are packaged to exact standards. Below is a summary of the core chemical and physical properties associated with this research compound:
| Parameter | Specification Detail |
| Catalog Name | CJC-1295 Without DAC (Mod GRF 1-29) |
| Unit Presentation | 10mg Lyophilized Powder |
| Molecular Formula | $C_{152}H_{252}N_{44}O_{42}$ |
| Molecular Weight | Approximately 3367.9 g/mol |
| Sequence Length | 29 Amino Acid Peptide Chain |
| CAS Number | 863288-34-0 |
| Formulation Type | Lyophilized Cake / Powder |
Uncompromised Quality Assurance: Tested for Purity, Weight, and Endotoxins (LPS)
At Global Peptides Lab, experimental integrity depends directly on the uncompromised quality of our catalog offerings. Every single production lot of CJC-1295 No DAC 10mg undergoes comprehensive, independent third-party analytical testing using high-performance liquid chromatography (HPLC) and mass spectrometry (MS) technologies.
Our stringent verification protocol screens for three critical parameters to guarantee research accuracy:
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Purity Validation: Confirmed at threshold levels of 99.0% or higher through rigorous chromatographic analysis, ensuring that secondary synthesis impurities or degraded peptide fragments do not confound experimental outcomes.
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Net Weight Verification: Analytical assay verification confirms that each production batch meets or exceeds the nominal 10mg mass specification, ensuring consistent molar concentrations upon solvent reconstitution.
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Endotoxin (LPS) Screening: Tested rigorously using kinetic chromogenic assays to ensure bacterial lipopolysaccharide (LPS) concentrations remain well below established safety thresholds (<0.001 EU/mg), protecting sensitive cellular cultures and in vitro models from inflammatory artifacts.
Handling, Reconstitution, and Storage Protocol
Proper laboratory stewardship is vital for preserving peptide stability and preventing structural degradation. Lyophilized powders should be stored in a controlled, dry environment at -20°C prior to opening. When preparing for experimental use, reconstitution should be performed using bacteriostatic water or sterile analytical solvents under a laminar flow hood, adhering strictly to aseptic handling techniques. Once reconstituted, solutions should be kept at refrigerated temperatures (2°C to 8°C) and utilized within strict experimental windows to maintain maximum structural integrity.
Why Partner With Global Peptides Lab?
Global Peptides Lab is dedicated to supporting the global scientific community by delivering uncompromised quality, full Certificate of Analysis (COA) transparency, and reliable worldwide distribution. Whether you are mapping complex endocrine pathways or evaluating comparative peptide dynamics, our commitment to analytical excellence ensures that every vial of CJC-1295 No DAC 10mg provides the reproducibility, purity, and scientific accuracy your research demands.
Disclaimer: All products supplied by Global Peptides Lab are strictly intended for laboratory research, in vitro analysis, and preclinical study only. They are not approved for human consumption, clinical trials, therapeutic use, or veterinary applications.




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